It is always important to stay up to date with all the new information coming out about medication as a pharmacist. In this article the authors summarized a review of 61 clinical trials on the use of NSAIDs for musculoskeletal conditions. Examples of the musculoskeletal conditions were sprain, strains, and contusions. These studies compared the NSAIDs against a placebo topical, another NSAID topical, and an oral NSAID.
Overall however the studies showed a definitive result that topical NSAIDs prove to be efficacious and show less side effects. The medication was applied directly on the skin above the painful area. Using a topical NSAID showed much less side effects because it avoids the gastrointestinal problems that usually come from NSAID use.
As I said earlier the conditions usually were sprains, strains, and contusions. This being said these types of injuries usually come from a younger group of people and for that reason a majority of the studies were done on healthy younger adults which could have skewed some results.
Although the summery concluded that the topical NSAIDs were efficacious and safe they authors did see the need for future studies. One area they would like to see future studies performed in is the dosing because they studies did not talk enough about dosing. It is difficult to accurately dose a topical medication, however it is still important for accurate research. They also called for studies in an older population to clarify if topical NSAIDs will still avoid the adverse effects associated with NSAIDs in an older population.
In summery I believe articles like this are very important for pharmacist and future pharmacist to read in order to stay up to date with all of the new medication and studies of medications. Pharmacist are expected to be medication experts and with this expectation they must always remain up to date all of the studies regarding medication.
Derry S, Wiffen P, Moore A. Topical Nonsteroidal Anti-inflammatory Drugs for Acute Musculoskeletal Pain. JAMA. 2016;315(8):813-814.